“The Family That Couldn’t Sleep” was quite interesting! It is hard to believe to know this disease can die within months. Science writer D.T. Max discussion about a family had a disease called fatal familial insomnia. Onset of the disease's symptoms, on average around middle age, sufferers become unable to sleep. They also try their best efforts to find a cure.

Here’s another issue I can think of…

When people said that the prospect the main issue of global warming was "real", they were absolutely promising some level of reliability. The intergovernmental panel on climate change was pressed to be as clear as possible about that. When the panel announced in 2001 that the present rate of warming was "very likely" larger than any seen within the last decades years, they responded to criticism of earlier reports by adding an annotation to define "very likely." They said it meant that they determined that there was a 90-99 percent chance that the result was true. The panel further determined it "likely” by which they meant a 66-90 percent chance of being true. The warming was mainly due to the increase of greenhouse gases. What it might mean to call a result "true" remain open to debate, philosophers have faithful their lifetimes to thinking how a scientific concept might somehow correspond to an eventual reality. That question rarely concerned climate scientists, who took it for granted that the future climate is as real as a rock, even if their knowledge of this future thing could only be confirmed within a range of probabilities.
Our human understanding of climate goes beyond scientific reports into a wider realm of thinking. When I look at a snowless street in January I may see a natural weather difference, or I may see a human object caused by greenhouse gas emissions. Such perceptions are twisted not only by scientists, but by interest groups, politicians, and the media. With global warming the social influences run deeper still. Unlike, say the orbits of planets, the future climate actually does depend in part on what we think about it. For what we think will determine what we do.